ChloroquineV1, Main, Exploration, bibRecord, 002F96

Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGG : studies on cultured glioma cells

Identifieur interne : 002F96 ( Main/Exploration ); précédent : 002F95; suivant : 002F97

Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGG : studies on cultured glioma cells

Auteurs : J. Capala [Suède] ; J. Carlsson

Source :

International journal of radiation biology [ 0955-3002 ] ; 1991.

RBID : Pascal:92-0245450

Descripteurs français

KwdFr :
- Cellules cultivées, Chloroquine (usage thérapeutique), Facteur de croissance épidermique (pharmacocinétique), Facteur de croissance épidermique (usage thérapeutique), Gliome (radiothérapie), Humains, Lidocaïne (usage thérapeutique), Radio-isotopes de l'iode (usage thérapeutique).
MESH :
- pharmacocinétique : Facteur de croissance épidermique.
- radiothérapie : Gliome.
- usage thérapeutique : Chloroquine, Facteur de croissance épidermique, Lidocaïne, Radio-isotopes de l'iode.
Pascal (Inist)
- Cellules cultivées, Humains, Irradiation ionisante, Facteur croissance épiderme, Récepteur biologique, Culture monocouche, Cellule tumorale, Gliome, Chloroquine, Lidocaïne, Radiothérapie, Radioisotope, Iode Complexe, Radiobiologie, Biophysique, Ciblage, Iode 131.
Wicri :
- topic : Radiobiologie.

English descriptors

KwdEn :
- Biological receptor, Biophysics, Cells, Cultured, Chloroquine (therapeutic use), Epidermal Growth Factor (pharmacokinetics), Epidermal Growth Factor (therapeutic use), Epidermal growth factor, Glioma, Glioma (radiotherapy), Humans, Iodine Complexes, Iodine Radioisotopes (therapeutic use), Ionizing irradiation, Lidocaine (therapeutic use), Monolayer culture, Radiobiology, Radioisotope, Radiotherapy, Tumor cell.
MESH :
- chemical , pharmacokinetics : Epidermal Growth Factor.
- chemical , therapeutic use : Chloroquine, Epidermal Growth Factor, Iodine Radioisotopes, Lidocaine.
- radiotherapy : Glioma.
- Cells, Cultured, Humans.

Abstract

Targeting of toxic substances to the epidermal growth factor, EGF, receptor might be an attractive therapeutic approach because of the increased receptor-expression in some human tumours such as, for example, malignant gliomas and squamous lung carcinomas. Radiation effects of [¹³¹I]EGF on human malignant glioma cells growing as monolayers were analysed in this study. The cells were, in all cases, incubated for 25 min with about 350 kBq/ml [¹³¹I]EGF, which gave a total binding of 3-2-3-5 kBq/10⁵ cells

Affiliations:

Suède

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Influence of chloroquine and lidocaine on retention and cytotoxic effects of [<sup>131</sup>
I]EGG : studies on cultured glioma cells</title>
<author><name sortKey="Capala, J" sort="Capala, J" uniqKey="Capala J" first="J." last="Capala">J. Capala</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Uppsala univ., dep. radiation sci.</s1>
<s2>Uppsala 751 21</s2>
<s3>SWE</s3>
</inist:fA14>
<country>Suède</country>
<wicri:noRegion>Uppsala 751 21</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Carlsson, J" sort="Carlsson, J" uniqKey="Carlsson J" first="J." last="Carlsson">J. Carlsson</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">92-0245450</idno>
<date when="1991">1991</date>
<idno type="stanalyst">PASCAL 92-0245450 INIST</idno>
<idno type="RBID">Pascal:92-0245450</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000099</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000071</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000098</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000098</idno>
<idno type="wicri:doubleKey">0955-3002:1991:Capala J:influence:of:chloroquine</idno>
<idno type="wicri:Area/Main/Merge">003063</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:1679089</idno>
<idno type="wicri:Area/PubMed/Corpus">000551</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000551</idno>
<idno type="wicri:Area/PubMed/Curation">000551</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000551</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000525</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000525</idno>
<idno type="wicri:Area/Ncbi/Merge">000090</idno>
<idno type="wicri:Area/Ncbi/Curation">000090</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000090</idno>
<idno type="wicri:doubleKey">0955-3002:1991:Capala J:influence:of:chloroquine</idno>
<idno type="wicri:Area/Main/Merge">002F58</idno>
<idno type="wicri:Area/Main/Curation">002F96</idno>
<idno type="wicri:Area/Main/Exploration">002F96</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Influence of chloroquine and lidocaine on retention and cytotoxic effects of [<sup>131</sup>
I]EGG : studies on cultured glioma cells</title>
<author><name sortKey="Capala, J" sort="Capala, J" uniqKey="Capala J" first="J." last="Capala">J. Capala</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Uppsala univ., dep. radiation sci.</s1>
<s2>Uppsala 751 21</s2>
<s3>SWE</s3>
</inist:fA14>
<country>Suède</country>
<wicri:noRegion>Uppsala 751 21</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Carlsson, J" sort="Carlsson, J" uniqKey="Carlsson J" first="J." last="Carlsson">J. Carlsson</name>
</author>
</analytic>
<series><title level="j" type="main">International journal of radiation biology</title>
<title level="j" type="abbreviated">Int. j. radiat. biol.</title>
<idno type="ISSN">0955-3002</idno>
<imprint><date when="1991">1991</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">International journal of radiation biology</title>
<title level="j" type="abbreviated">Int. j. radiat. biol.</title>
<idno type="ISSN">0955-3002</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biological receptor</term>
<term>Biophysics</term>
<term>Cells, Cultured</term>
<term>Chloroquine (therapeutic use)</term>
<term>Epidermal Growth Factor (pharmacokinetics)</term>
<term>Epidermal Growth Factor (therapeutic use)</term>
<term>Epidermal growth factor</term>
<term>Glioma</term>
<term>Glioma (radiotherapy)</term>
<term>Humans</term>
<term>Iodine Complexes</term>
<term>Iodine Radioisotopes (therapeutic use)</term>
<term>Ionizing irradiation</term>
<term>Lidocaine (therapeutic use)</term>
<term>Monolayer culture</term>
<term>Radiobiology</term>
<term>Radioisotope</term>
<term>Radiotherapy</term>
<term>Tumor cell</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Cellules cultivées</term>
<term>Chloroquine (usage thérapeutique)</term>
<term>Facteur de croissance épidermique (pharmacocinétique)</term>
<term>Facteur de croissance épidermique (usage thérapeutique)</term>
<term>Gliome (radiothérapie)</term>
<term>Humains</term>
<term>Lidocaïne (usage thérapeutique)</term>
<term>Radio-isotopes de l'iode (usage thérapeutique)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Epidermal Growth Factor</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Chloroquine</term>
<term>Epidermal Growth Factor</term>
<term>Iodine Radioisotopes</term>
<term>Lidocaine</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacocinétique" xml:lang="fr"><term>Facteur de croissance épidermique</term>
</keywords>
<keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en"><term>Glioma</term>
</keywords>
<keywords scheme="MESH" qualifier="radiothérapie" xml:lang="fr"><term>Gliome</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Chloroquine</term>
<term>Facteur de croissance épidermique</term>
<term>Lidocaïne</term>
<term>Radio-isotopes de l'iode</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Cells, Cultured</term>
<term>Humans</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Cellules cultivées</term>
<term>Humains</term>
<term>Irradiation ionisante</term>
<term>Facteur croissance épiderme</term>
<term>Récepteur biologique</term>
<term>Culture monocouche</term>
<term>Cellule tumorale</term>
<term>Gliome</term>
<term>Chloroquine</term>
<term>Lidocaïne</term>
<term>Radiothérapie</term>
<term>Radioisotope</term>
<term>Iode Complexe</term>
<term>Radiobiologie</term>
<term>Biophysique</term>
<term>Ciblage</term>
<term>Iode 131</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Radiobiologie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Targeting of toxic substances to the epidermal growth factor, EGF, receptor might be an attractive therapeutic approach because of the increased receptor-expression in some human tumours such as, for example, malignant gliomas and squamous lung carcinomas. Radiation effects of [<sup>131</sup>
I]EGF on human malignant glioma cells growing as monolayers were analysed in this study. The cells were, in all cases, incubated for 25 min with about 350 kBq/ml [<sup>131</sup>
I]EGF, which gave a total binding of 3-2-3-5 kBq/10<sup>5</sup>
 cells</div>
</front>
</TEI>
<affiliations><list><country><li>Suède</li>
</country>
</list>
<tree><noCountry><name sortKey="Carlsson, J" sort="Carlsson, J" uniqKey="Carlsson J" first="J." last="Carlsson">J. Carlsson</name>
</noCountry>
<country name="Suède"><noRegion><name sortKey="Capala, J" sort="Capala, J" uniqKey="Capala J" first="J." last="Capala">J. Capala</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002F96 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002F96 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:92-0245450
   |texte=   Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGG : studies on cultured glioma cells
}}

This area was generated with Dilib version V0.6.33.
Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021

Serveur d'exploration Chloroquine

Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGG : studies on cultured glioma cells

Influence of chloroquine and lidocaine on retention and cytotoxic effects of [131I]EGG : studies on cultured glioma cells

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration Chloroquine
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.